Speaker
Description
Iron nanoparticles have emerged as a promising frontier in the realm of nanomedicine, offering unprecedented potential for revolutionizing diagnostics, imaging, targeting, drug delivery, and therapy [1]. Their unique physicochemical properties, such as high surface area-to-volume ratio, tunable magnetic properties, and biocompatibility, make them ideal candidates for various biomedical applications [2].
We have prepared the nanoparticle system consisting of Fe$_3$O$_4$ magnetic core coated with a silica SiO$_2$ shell with a size of approximately 10 nm. Such system was detailly analyzed in terms of magnetic properties. In Fig. 1 the magnetization measurement in ZFC/FC mode at applied external magnetic field of 100 Oe is presented.
Fig. 1 Magnetic measurements in ZFC/FC mode at applied external magnetic field of 100 Oe.
Magnetic properties of the system have been examined in AC and DC conditions. Isothermal magnetization data taken at temperature span 5-300 K confirmed superparamagnetic behavior of the system above 50 K. The series of ZFC-FC measurements under various applied DC fields revealed field dependence of blocking temperature and signatures of interparticle interactions in the system. The strength of the interactions has been determined by means of various methods. The construction of Henkel plot points to the dipole-dipole origin of the magnetic interactions. Neel-Arrhenius, Vogel-Fulcher and the Critical slowing down models have been applied to the collected AC magnetic susceptibility vs temperature data. The analysis reconfirmed the presence of intermediate/strong interparticle interactions in accordance with the results obtained from DC data.
Acknowledgements
This work was supported by the Slovak Research and Development Agency under the contract APVV-20-0512 and by the Operational Programme Integrated Infrastructure, project “NANOVIR”, ITMS:313011AUW7, co-funded by ERDF.
References
[1] P. Farinha, J. M. P. Coelho, C. P. Reis, and M. M. Gaspar, “A Comprehensive Updated Review on Magnetic Nanoparticles in Diagnostics,” Nanomaterials, vol. 11, no. 12. MDPI AG, p. 3432, Dec. 17, 2021. doi: 10.3390/nano11123432.
[2] N. Elahi and M. Rizwan, “Progress and prospects of magnetic iron oxide nanoparticles in biomedical applications: A review,” Artificial Organs, vol. 45, no. 11. Wiley, pp. 1272–1299, Jul. 09, 2021. doi: 10.1111/aor.14027.
